Dr. Leroy Young et al's study on bacterial and fungal
Date: Sat, 01 Apr 2000 14:52:36 GMT
From: ICE
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delphine1939@videotron.caNewsgroups: alt.support.breast-implant
Plastic & Reconstructive Surgery Journal, July 1997.
Dr. Leroy Young et al's study on bacterial and fungal growth in implants.
Plastic & Reconstructive Surgery Journal, July 1997.
Dr. Leroy Young et al's study on bacterial and fungal growth in implants.
Here are just a few comments under Discussion:
Although the study reported here confirms the investigations of others regarding organisms present around breast implants, both our in vivo (in live bunny rabbits) and in vitro (sterile bottles) experiments more importantly demonstrate that several species of bacteria and fungi can survive and multiply in the intraluminal saline of b.i. for prolonged periods.... Microbes may be able to survive and even reproduce in sterile saline without nutrients for a limited time period, or they might support their growth briefly by ingesting the cellular components of other organisms that have died... For longer term survival, it seems likely that nutrients are able to gain access to the intraluminal environment be means of diffusion through the elastomer implant shell...Even tho an implnt's envelope has been assumed to be impermeable to diffusion by ions and small molecules because of the elastomer's hydrophobic polymer structure, this assumption has not been tested historically.... In one patient with bilateral implants that were culture positive for Aspergillus niger, the fungus was cultured from the saline, the capsular tissue, and the intracapsular space which contained a cheesy white exudate If nutritional substrates can diffuse into an implant, then it follows that toxic metabolites produced by intraluminal organisms can diffuse out. Toxic products from microoganisms also could be released into the bodyshould a contaminated saline implant fail... .Unfortunately, our finding that intraluminal saline is not resistant to several species of bacteria and fungi raises a whole new series of difficult questions...
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These rabbits were implanted no more than 6 months.